BBPvsPSCHETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. Invesco S&P SmallCap Health Care ETF (PSCH) is part of the US Health Care segment. Both ETFs have the same top 1 sector exposures: Healthcare. BBP is more expensive with a Total Expense Ratio (TER) of 0.34%, versus 0.29% for PSCH. BBP is up 28.37% year-to-date (YTD) with +$66M in YTD flows. PSCH performs worse with 23.3% YTD performance, and -$1M in YTD flows. Run a side-by-side ETF comparison of BBP and PSCH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs PSCH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/26/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP PSCH | -2.65%+1.90% | +5.62%+2.74% | +28.37%+23.30% | +38.01%+27.01% | +119.28%+55.14% | +100.33%-8.77% |
| Flows | BBP PSCH | --$11M | +$26M+$9M | +$66M-$1M | +$78M-$921K | +$83M-$102M | +$76M-$210M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP PSCH | +28.32%+17.03% | +26.44%+19.47% | +24.98%+21.78% | +26.86%+22.92% |
| Max drawdown | BBP PSCH | -8.70%-8.61% | -9.59%-15.36% | -25.54%-22.80% | -37.61%-45.76% |
| Max drawdown duration | BBP PSCH | 68d68d | 48d168d | 292d488d | 586d1813d |
Trading data
BBP | PSCH | |
Last sale 10/27/2026 at 1:30 PM | $104.89 | $54.75 |
| Previous close 10/26/2026 | $102.33 | $54.35 |
| Consolidated volume 10/26/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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BBP | PSCH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/27/2026 at 1:30 PM
Live
Closed
BBP | PSCH | |
|---|---|---|
| Last price | $104.89 | $54.75 |
| 1D performance | +2.50% | +0.74% |
| AuM | $127.99 M | $175.03 M |
| E/R | 0.34% | 0.29% |
Characteristics
BBP | PSCH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | Invesco |
| Benchmark | LifeSci Biotechnology Products Index | S&P SmallCap 600 Capped Health Care Index |
| N° of holdings | 66 | 69 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | April 7, 2010 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
85.98%
Other
14.02%
PSCH
USA
94.93%
Other
5.07%
Sectors
BBP
Healthcare
98.44%
Other
1.56%
PSCH
Healthcare
100%
Other
0%
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Diversification
BBP
Total weight of top 15 holdings out of 15
31.08%
PSCH
Total weight of top 15 holdings out of 15
48.62%
Top 15 holdings
Data as of August 31, 2026
BBP
Moderna, Inc.
3.58%
Crinetics Pharmaceuticals, Inc.
2.94%
Omeros Corp.
2.49%
Iovance Biotherapeutics, Inc.
2.36%
Verastem, Inc.
2.15%
Precigen, Inc.
1.99%
Halozyme Therapeutics, Inc.
1.84%
Zai Lab Ltd.
1.82%
Kiniksa Pharmaceuticals International Plc
1.81%
Kura Oncology, Inc.
1.72%
BeOne Medicines Ltd.
1.70%
Rigel Pharmaceuticals, Inc.
1.69%
Nuvation Bio, Inc.
1.69%
ACADIA Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
PSCH
Corcept Therapeutics, Inc.
5.61%
Glaukos Corp.
5.37%
Protagonist Therapeutics, Inc.
4.54%
Alkermes Plc
4.09%
TG Therapeutics, Inc.
3.69%
Teleflex, Inc.
3.06%
PTC Therapeutics, Inc.
2.99%
Ligand Pharmaceuticals, Inc.
2.87%
Merit Medical Systems, Inc.
2.68%
RadNet, Inc.
2.68%
Liquidia Corp.
2.47%
ICU Medical, Inc.
2.20%
Indivior Pharmaceuticals, Inc.
2.16%
Integer Holdings Corp.
2.14%
Concentra Group Holdings Parent, Inc.
2.07%
Frequently asked questions about BBP and PSCH
How have the BBP and PSCH ETFs performed in 2026?
As of October 26, 2026, BBP is up 28.37% year-to-date (YTD), while PSCH has returned 23.3%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or PSCH?
Year-to-date, the BBP ETF saw +$66M in flows, compared to -$1M for PSCH.
Which ETF is more volatile: BBP or PSCH?
Over the past year, BBP had a volatility of 26.44%, while PSCH experienced 19.47%.
Which ETF is bigger: BBP or PSCH?
As of October 26, 2026, BBP holds $127.99 M in assets under management (AUM), while PSCH manages $175.03 M.
What sectors do the BBP and PSCH ETFs invest in?
BBP leans toward sectors like Healthcare. Meanwhile, PSCH focuses on Healthcare.
What are the top holdings of the BBP ETF and PSCH ETF?
BBP top holdings include Moderna, Inc., Crinetics Pharmaceuticals, Inc. and Omeros Corp.. PSCH holds in its top three: Corcept Therapeutics, Inc., Glaukos Corp. and Protagonist Therapeutics, Inc..
Which ETF is more diversified: BBP or PSCH?
BBP holds 66 securities with 31.08% of its assets in the top 15. PSCH has 69 securities and a top 15 weight of 48.62%.
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