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BBPvsPSCHETF Comparison

ETF 1
BBP

Virtus LifeSci Biotech Products ETF

This fund is part of
Tomorrow's Treatments
-0.71%
VS
ETF 2
PSCH

Invesco S&P SmallCap Health Care ETF

This fund is part of
US Health Care
-0.12%

Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. Invesco S&P SmallCap Health Care ETF (PSCH) is part of the US Health Care segment. Both ETFs have the same top 1 sector exposures: Healthcare. BBP is more expensive with a Total Expense Ratio (TER) of 0.34%, versus 0.29% for PSCH. BBP is up 29.59% year-to-date (YTD) with +$61M in YTD flows. PSCH performs worse with 20.58% YTD performance, and +$7M in YTD flows. Run a side-by-side ETF comparison of BBP and PSCH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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BBP vs PSCH performance and flow charts

Performance

-4.0-2.00.02.04.06.08.0%Aug 10Aug 17Aug 24Aug 31Sep 7

Cumulative Flows

0 M5 M10 M15 MAug 10Aug 17Aug 24Aug 31Sep 7

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Historic performance and flows
Data as of 09/11/2026
1M3MYTD1Y3Y5Y
Perf.
BBP
PSCH
+1.58%-3.91%
+19.06%+12.71%
+29.59%+20.58%
+46.60%+31.06%
+94.97%+34.64%
+99.54%-14.13%
Flows
BBP
PSCH
+$16M+$14M
+$31M+$25M
+$61M+$7M
+$72M+$2M
+$78M-$109M
+$71M-$207M
Volatility and drawdown
3M1Y3Y5Y
Volatility
BBP
PSCH
+25.64%+15.88%
+25.15%+19.61%
+24.71%+21.82%
+26.61%+22.87%
Max drawdown
BBP
PSCH
-9.34%-5.28%
-9.59%-15.36%
-25.54%-22.80%
-37.61%-45.76%
Max drawdown duration
BBP
PSCH
39d22d
48d168d
292d488d
586d1767d
Trading data

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BBP
PSCH
Last sale
9/11/2026 at 1:30 PM
$103.46
$52.95
Previous close
09/10/2026
$103.47
$53.11
Consolidated volume
09/10/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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BBP
PSCH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
BBP
PSCH
Last price
$103.46
$52.95
1D performance
-0.01%
-0.30%
AuM$124.03 M$179.68 M
E/R0.34%0.29%
Characteristics
BBP
PSCH
Management strategyPassivePassive
ProviderVIRTUS Investment PartnersInvesco
BenchmarkLifeSci Biotechnology Products IndexS&P SmallCap 600 Capped Health Care Index
N° of holdings6669
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateDecember 16, 2014April 7, 2010
ESGNoNo
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Exposure

Countries

BBP
USA
86.5%
Other
13.5%
PSCH
USA
95.04%
Other
4.96%

Sectors

BBP
Healthcare
98.2%
Other
1.8%
PSCH
Healthcare
100%
Other
0%
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Diversification

BBP

Total weight of top 15 holdings out of 15

26.78%
PSCH

Total weight of top 15 holdings out of 15

48.1%

Top 15 holdings

Data as of July 31, 2026
BBP
Crinetics Pharmaceuticals, Inc.
3.24%
Verastem, Inc.
1.98%
Nuvation Bio, Inc.
1.80%
Omeros Corp.
1.73%
Geron Corp.
1.72%
BridgeBio Pharma, Inc.
1.68%
Agios Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
BeOne Medicines Ltd.
1.64%
Kiniksa Pharmaceuticals International Plc
1.63%
Precigen, Inc.
1.62%
Xeris Biopharma Holdings, Inc.
1.61%
ACADIA Pharmaceuticals, Inc.
1.60%
Iovance Biotherapeutics, Inc.
1.60%
Rhythm Pharmaceuticals, Inc.
1.60%
PSCH
Glaukos Corp.
4.96%
Corcept Therapeutics, Inc.
4.64%
Alkermes Plc
4.21%
Protagonist Therapeutics, Inc.
4.20%
TG Therapeutics, Inc.
3.68%
PTC Therapeutics, Inc.
3.23%
Liquidia Corp.
3.19%
Teleflex, Inc.
3.11%
Ligand Pharmaceuticals, Inc.
3.01%
Indivior Pharmaceuticals, Inc.
2.55%
Merit Medical Systems, Inc.
2.52%
RadNet, Inc.
2.34%
Veracyte, Inc.
2.32%
ICU Medical, Inc.
2.17%
Concentra Group Holdings Parent, Inc.
1.96%
Frequently asked questions about BBP and PSCH

How have the BBP and PSCH ETFs performed in 2026?

As of September 11, 2026, BBP is up 29.59% year-to-date (YTD), while PSCH has returned 20.58%. That puts BBP better performer ahead so far this year.

Which ETF is attracting more investor money: BBP or PSCH?

Year-to-date, the BBP ETF saw +$61M in flows, compared to +$7M for PSCH.

Which ETF is more volatile: BBP or PSCH?

Over the past year, BBP had a volatility of 25.15%, while PSCH experienced 19.61%.

Which ETF is bigger: BBP or PSCH?

As of September 11, 2026, BBP holds $124.03 M in assets under management (AUM), while PSCH manages $179.68 M.

What sectors do the BBP and PSCH ETFs invest in?

BBP leans toward sectors like Healthcare. Meanwhile, PSCH focuses on Healthcare.

What are the top holdings of the BBP ETF and PSCH ETF?

BBP top holdings include Crinetics Pharmaceuticals, Inc., Verastem, Inc. and Nuvation Bio, Inc.. PSCH holds in its top three: Glaukos Corp., Corcept Therapeutics, Inc. and Alkermes Plc.

Which ETF is more diversified: BBP or PSCH?

BBP holds 66 securities with 26.78% of its assets in the top 15. PSCH has 69 securities and a top 15 weight of 48.1%.

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