Keep tabs on your favorite ETFs with a personalized weekly tracker. Create a Watchlist now →
BBPvsPBEETF Comparison
Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.58% for PBE. BBP is up 5.62% year-to-date (YTD) with +$4M in YTD flows. PBE performs worse with -7.12% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of BBP and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
BBP vs PBE performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP PBE | +2.73%-6.52% | +7.35%-5.52% | +5.62%-7.12% | +41.19%+19.22% | +72.79%+26.51% | +54.18%+1.84% |
| Flows | BBP PBE | +$4M-$3M | +$16M+$969K | +$4M+$135K | +$19M-$32M | +$19M-$56M | +$9M-$39M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP PBE | +24.64%+18.95% | +25.49%+22.28% | +23.37%+20.18% | +26.10%+22.77% |
| Max drawdown | BBP PBE | -7.42%-11.05% | -17.97%-16.18% | -25.54%-22.21% | -38.24%-34.74% |
| Max drawdown duration | BBP PBE | 32d65d | 106d107d | 292d324d | 915d1540d |
BBP | PBE | |
Last sale 3/13/2026 at 1:30 PM | $81.25 | $76.18 |
| Previous close 03/12/2026 | $81.68 | $76.18 |
| Consolidated volume 03/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Create an account to view replication metrics
BBP | PBE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
BBP | PBE | |
|---|---|---|
| Last price | $81.25 | $76.18 |
| 1D performance | -0.53% | +0.00% |
| AuM | $50.55 M | $240.98 M |
| E/R | 0.79% | 0.58% |
BBP | PBE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | Invesco |
| Benchmark | LifeSci Biotechnology Products Index | Dynamic Biotech & Genome Intellidex Index |
| N° of holdings | 58 | 30 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | June 23, 2005 |
| ESG | No | No |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the BBP and PBE ETFs performed in 2026?
As of March 11, 2026, BBP is up 5.62% year-to-date (YTD), while PBE has lost -7.12%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or PBE?
Year-to-date, the BBP ETF saw +$4M in flows, compared to +$135K for PBE.
Which ETF is more volatile: BBP or PBE?
Over the past year, BBP had a volatility of 25.49%, while PBE experienced 22.28%.
Which ETF is bigger: BBP or PBE?
As of March 11, 2026, BBP holds $50.55 M in assets under management (AUM), while PBE manages $240.98 M.
What sectors do the BBP and PBE ETFs invest in?
BBP leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.
What are the top holdings of the BBP ETF and PBE ETF?
BBP top holdings include DAY ONE BIOPHARMACEUTICALS, DYNAVAX TECHNOLOGIES and AMICUS THERAPEUTICS. PBE holds in its top three: ILLUMINA, GILEAD SCIENCES and AMGEN-T.
Which ETF is more diversified: BBP or PBE?
BBP holds 63 securities with 30.11% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.48%.
Active Trader Report: Use of Leveraged & Inverse ETFs Way Up
Direxion partnered with Compound Insights and Vanda to explore what’s driving the evolution of active trading — and how active traders are using leveraged and inverse funds across equities, single stocks, commodities, and volatility.
