BBPvsPBEETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.58% for PBE. BBP is up 9.25% year-to-date (YTD) with +$30M in YTD flows. PBE performs worse with 2.54% YTD performance, and -$3M in YTD flows. Run a side-by-side ETF comparison of BBP and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs PBE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP PBE | -1.38%+1.33% | +7.00%+10.39% | +9.25%+2.54% | +43.65%+31.31% | +60.05%+34.96% | +58.90%+10.44% |
| Flows | BBP PBE | +$4M+$2M | +$26M-$3M | +$30M-$3M | +$42M-$26M | +$45M-$56M | +$38M-$45M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP PBE | +28.75%+19.82% | +24.06%+19.09% | +24.00%+20.14% | +26.36%+22.41% |
| Max drawdown | BBP PBE | -7.49%-4.08% | -9.59%-11.70% | -25.54%-22.21% | -37.87%-34.74% |
| Max drawdown duration | BBP PBE | 37d16d | 48d156d | 292d324d | 760d1540d |
Trading data
BBP | PBE | |
Last sale 6/12/2026 at 1:30 PM | $87.17 | $84.10 |
| Previous close 06/11/2026 | $86.80 | $84.82 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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BBP | PBE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
BBP | PBE | |
|---|---|---|
| Last price | $87.17 | $84.10 |
| 1D performance | +0.42% | -0.85% |
| AuM | $78.43 M | $259.85 M |
| E/R | 0.79% | 0.58% |
Characteristics
BBP | PBE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | Invesco |
| Benchmark | LifeSci Biotechnology Products Index | Dynamic Biotech & Genome Intellidex Index |
| N° of holdings | 55 | 30 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | June 23, 2005 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
84.13%
Other
15.87%
PBE
USA
92.2%
Other
7.8%
Sectors
BBP
Health Care
85.97%
Other
14.03%
PBE
Health Care
97.78%
Other
2.22%
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Diversification
BBP
Total weight of top 15 holdings out of 15
45.32%
PBE
Total weight of top 15 holdings out of 15
62.95%
Top 15 holdings
Data as of April 30, 2026
BBP
ARROWHEAD PHARMACEUTICALS INC
3.17%
GB00BRXB0C07
3.17%
BIOGEN INC
3.14%
HALOZYME THERAPEUTICS
3.13%
AURINIA PHARMACEUTICALS INC
3.12%
SYNDAX PHARMACEUTICALS INC
3.12%
BIOMARIN PHARMACEUTICAL
3.05%
INCYTE
3.03%
REGENERON PHARMACEUTICALS
3.03%
BRIDGEBIO PHARMA
3.00%
SAREPTA THERAPEUTICS INC DE
2.95%
ARDELYX
2.92%
VERTEX PHARMACEUTICALS
2.85%
US07725L1026
2.83%
THERAVANCE BIOPHARMA
2.80%
PBE
UTD THERAPEUT
6.20%
ILLUMINA
5.42%
REGENERON PHARMACEUTICALS
4.99%
INCYTE
4.91%
ALNYLAM PHARMACEUTICALS
4.80%
BIOGEN INC
4.80%
AMGEN-T
4.60%
GILEAD SCIENCES
4.48%
CATALYST PHARMACEUTICALS INC
3.42%
BIOCRYST PHARMACEUTICALS
3.30%
TG THERAPEUTICS
3.28%
ARROWHEAD PHARMACEUTICALS INC
3.27%
CAREDX INC/D
3.21%
PROTAGONIST THERAPEUTICS INC
3.18%
ROYALTY PHARMA
3.09%
Frequently asked questions about BBP and PBE
How have the BBP and PBE ETFs performed in 2026?
As of June 12, 2026, BBP is up 9.25% year-to-date (YTD), while PBE has returned 2.54%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or PBE?
Year-to-date, the BBP ETF saw +$30M in flows, compared to -$3M for PBE.
Which ETF is more volatile: BBP or PBE?
Over the past year, BBP had a volatility of 24.06%, while PBE experienced 19.09%.
Which ETF is bigger: BBP or PBE?
As of June 12, 2026, BBP holds $78.43 M in assets under management (AUM), while PBE manages $259.85 M.
What sectors do the BBP and PBE ETFs invest in?
BBP leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.
What are the top holdings of the BBP ETF and PBE ETF?
BBP top holdings include ARROWHEAD PHARMACEUTICALS INC, GB00BRXB0C07 and BIOGEN INC. PBE holds in its top three: UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS.
Which ETF is more diversified: BBP or PBE?
BBP holds 59 securities with 45.32% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 62.95%.
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