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BBPvsLFSCETF Comparison

ETF 1
BBP

Virtus LifeSci Biotech Products ETF

This fund is part of
Tomorrow's Treatments
-2.17%
Full BBP fund page
VS
ETF 2
LFSC

F/m Emerald Life Sciences Innovation ETF

This fund is part of
Life Sciences
-3.41%
Full LFSC fund page

Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. F/m Emerald Life Sciences Innovation ETF (LFSC) is part of the Life Sciences segment. Both ETFs have the same top 3 sector exposures: and Health Care. Both BBP and LFSC have the same Total Expense Ratio (TER) of 0.79%. BBP is up 5.62% year-to-date (YTD) with +$4M in YTD flows. LFSC performs worse with -7.57% YTD performance, and +$5M in YTD flows. Run a side-by-side ETF comparison of BBP and LFSC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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BBP vs LFSC performance and flow charts

Performance

-6.0-4.0-2.00.02.04.06.0%Feb 11Feb 19Feb 26Mar 5Mar 12

Cumulative Flows

0 M2 M4 M6 M8 MFeb 11Feb 19Feb 26Mar 5Mar 12

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Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
BBP
LFSC
+2.73%-5.12%
+7.35%-13.36%
+5.62%-7.57%
+41.19%+48.56%
+72.79%n/a
+54.18%n/a
Flows
BBP
LFSC
+$4M+$6M
+$16M+$6M
+$4M+$5M
+$19M+$16M
+$19M-
+$9M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
BBP
LFSC
+24.64%+22.88%
+25.49%+28.76%
+23.37%n/a
+26.10%n/a
Max drawdown
BBP
LFSC
-7.42%-13.77%
-17.97%-19.03%
-25.54%n/a
-38.24%n/a
Max drawdown duration
BBP
LFSC
32d77d
106d70d
292dn/a
915dn/a
Trading data

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BBP
LFSC
Last sale
3/13/2026 at 1:30 PM
$81.25
$33.61
Previous close
03/12/2026
$81.68
$33.82
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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LFSC
is actively managed and doesn’t replicate an index

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BBP
LFSC
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
BBP
LFSC
Last price
$81.25
$33.61
1D performance
-0.53%
-0.62%
AuM$50.55 M$90.59 M
E/R0.79%0.79%
Characteristics
BBP
LFSC
Management strategyPassiveActive
ProviderVIRTUS Investment PartnersEmerald Group
BenchmarkLifeSci Biotechnology Products Index-
N° of holdings5834
Asset classEquities-
Trailing 12m distribution yield
Join
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Inception dateDecember 16, 2014October 31, 2024
ESGNoNo
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Exposure

Countries

BBP
USA
90.82%
Other
9.18%
LFSC
USA
88.44%
Other
11.56%

Sectors

BBP
Health Care
88.88%
Other
11.12%
LFSC
Health Care
86.26%
Other
13.74%
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Diversification

BBP

Total weight of top 15 holdings out of 15

30.11%
LFSC

Total weight of top 15 holdings out of 15

68.94%

Top 15 holdings

Data as of January 31, 2026
BBP
DAY ONE BIOPHARMACEUTICALS
2.39%
DYNAVAX TECHNOLOGIES
2.39%
AMICUS THERAPEUTICS
2.25%
IOVANCE BIOTHERAPEUTICS INC
2.18%
ARDELYX
2.09%
AXSOME THERA CMN STK
2.07%
BIONTECH SE ADR
2.07%
GILEAD SCIENCES
1.90%
KRYSTAL BIOTECH INC
1.89%
HALOZYME THERAPEUTICS
1.86%
US52635N1037
1.85%
AMGEN-T
1.83%
THERAVANCE BIOPHARMA
1.80%
INCYTE
1.78%
EXELIXIS
1.77%
LFSC
COGENT BIOSCIENCES
9.06%
LIVANOVA
6.76%
GUARDANT HEALTH INC
5.62%
MIRUM PHARMACEUTICALS INC
5.37%
TRANSMEDICS GROUP
5.18%
WAVE LFE SCIEN
4.81%
TRAVERE THERAPEUTICS INC
4.77%
BRIDGEBIO PHARMA
3.92%
SAVARA INC
3.82%
ICU MEDICAL
3.60%
KALVISTA PHARMACEUTICALS INC
3.59%
UTD THERAPEUT
3.56%
US00773J2024
3.44%
MADRIGAL PHARMACEUTICALS INC
2.86%
ACADIA PHARMACEUTICALS
2.58%
Frequently asked questions about BBP and LFSC

How have the BBP and LFSC ETFs performed in 2026?

As of March 11, 2026, BBP is up 5.62% year-to-date (YTD), while LFSC has lost -7.57%. That puts BBP better performer ahead so far this year.

Which ETF is attracting more investor money: BBP or LFSC?

Year-to-date, the BBP ETF saw +$4M in flows, compared to +$5M for LFSC.

Which ETF is more volatile: BBP or LFSC?

Over the past year, BBP had a volatility of 25.49%, while LFSC experienced 28.76%.

Which ETF is bigger: BBP or LFSC?

As of March 11, 2026, BBP holds $50.55 M in assets under management (AUM), while LFSC manages $90.59 M.

What sectors do the BBP and LFSC ETFs invest in?

BBP leans toward sectors like Health Care. Meanwhile, LFSC focuses on Health Care.

What are the top holdings of the BBP ETF and LFSC ETF?

BBP top holdings include DAY ONE BIOPHARMACEUTICALS, DYNAVAX TECHNOLOGIES and AMICUS THERAPEUTICS. LFSC holds in its top three: COGENT BIOSCIENCES, LIVANOVA and GUARDANT HEALTH INC.

Which ETF is more diversified: BBP or LFSC?

BBP holds 63 securities with 30.11% of its assets in the top 15. LFSC has 42 securities and a top 15 weight of 68.94%.

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