BBPvsHELXETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. Franklin Genomic Advancements ETF (HELX) is part of the BioTech & Genomics segment. BBP's top 1 sector exposures are Healthcare. In contrast, HELX's top sector exposures are Healthcare, Non-Energy Materials and Technology. BBP is less expensive with a Total Expense Ratio (TER) of 0.34%, versus 0.5% for HELX. BBP is up 29.77% year-to-date (YTD) with +$50M in YTD flows. HELX performs worse with 13.15% YTD performance, and +$6M in YTD flows. Run a side-by-side ETF comparison of BBP and HELX below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs HELX performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/10/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP HELX | +2.31%-1.65% | +22.34%+17.45% | +29.77%+13.15% | +48.76%+36.43% | +95.24%+37.63% | +99.54%-28.62% |
| Flows | BBP HELX | +$5M- | +$20M+$4M | +$50M+$6M | +$62M+$8M | +$68M+$15M | +$61M+$4M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP HELX | +26.03%+24.64% | +25.17%+22.94% | +24.72%+21.44% | +26.61%+23.58% |
| Max drawdown | BBP HELX | -9.34%-6.59% | -9.59%-17.89% | -25.54%-29.16% | -37.61%-58.16% |
| Max drawdown duration | BBP HELX | 39d28d | 48d206d | 292d458d | 586d1813d |
Trading data
BBP | HELX | |
Last sale 9/11/2026 at 1:30 PM | $103.46 | $40.99 |
| Previous close 09/10/2026 | $103.47 | $41.03 |
| Consolidated volume 09/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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HELX
is actively managed and doesn’t replicate an indexBBP | HELX | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
BBP | HELX | |
|---|---|---|
| Last price | $103.46 | $40.99 |
| 1D performance | -0.01% | -0.11% |
| AuM | $113.85 M | $30.79 M |
| E/R | 0.34% | 0.5% |
Characteristics
BBP | HELX | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VIRTUS Investment Partners | Franklin Templeton |
| Benchmark | LifeSci Biotechnology Products Index | - |
| N° of holdings | 66 | 66 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | February 25, 2020 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
86.5%
Other
13.5%
HELX
USA
86.99%
Other
13.01%
Sectors
BBP
Healthcare
98.2%
Other
1.8%
HELX
Healthcare
96.35%
Other
3.65%
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Diversification
BBP
Total weight of top 15 holdings out of 15
26.78%
HELX
Total weight of top 15 holdings out of 15
60.19%
Top 15 holdings
Data as of July 31, 2026
BBP
Crinetics Pharmaceuticals, Inc.
3.24%
Verastem, Inc.
1.98%
Nuvation Bio, Inc.
1.80%
Omeros Corp.
1.73%
Geron Corp.
1.72%
BridgeBio Pharma, Inc.
1.68%
Agios Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
BeOne Medicines Ltd.
1.64%
Kiniksa Pharmaceuticals International Plc
1.63%
Precigen, Inc.
1.62%
Xeris Biopharma Holdings, Inc.
1.61%
ACADIA Pharmaceuticals, Inc.
1.60%
Iovance Biotherapeutics, Inc.
1.60%
Rhythm Pharmaceuticals, Inc.
1.60%
HELX
Guardant Health, Inc.
9.10%
Natera, Inc.
7.31%
Krystal Biotech, Inc.
6.17%
Ligand Pharmaceuticals, Inc.
4.48%
Adaptive Biotechnologies Corp.
4.33%
BridgeBio Pharma, Inc.
4.08%
United Therapeutics Corp.
3.52%
Eli Lilly & Co.
3.04%
Vertex Pharmaceuticals, Inc.
2.73%
SAMSUNG BIOLOGICS Co., Ltd.
2.72%
Travere Therapeutics, Inc.
2.67%
Corteva, Inc.
2.65%
AstraZeneca PLC
2.49%
Twist Bioscience Corp.
2.47%
Medpace Holdings, Inc.
2.44%
Frequently asked questions about BBP and HELX
How have the BBP and HELX ETFs performed in 2026?
As of September 10, 2026, BBP is up 29.77% year-to-date (YTD), while HELX has returned 13.15%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or HELX?
Year-to-date, the BBP ETF saw +$50M in flows, compared to +$6M for HELX.
Which ETF is more volatile: BBP or HELX?
Over the past year, BBP had a volatility of 25.17%, while HELX experienced 22.94%.
Which ETF is bigger: BBP or HELX?
As of September 10, 2026, BBP holds $113.85 M in assets under management (AUM), while HELX manages $30.79 M.
What sectors do the BBP and HELX ETFs invest in?
BBP leans toward sectors like Healthcare. Meanwhile, HELX focuses on Healthcare.
What are the top holdings of the BBP ETF and HELX ETF?
BBP top holdings include Crinetics Pharmaceuticals, Inc., Verastem, Inc. and Nuvation Bio, Inc.. HELX holds in its top three: Guardant Health, Inc., Natera, Inc. and Krystal Biotech, Inc..
Which ETF is more diversified: BBP or HELX?
BBP holds 66 securities with 26.78% of its assets in the top 15. HELX has 66 securities and a top 15 weight of 60.19%.
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