BBPvsHELXETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. Franklin Genomic Advancements ETF (HELX) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.5% for HELX. BBP is up 9.25% year-to-date (YTD) with +$30M in YTD flows. HELX performs worse with -2.29% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of BBP and HELX below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs HELX performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP HELX | -1.38%+4.54% | +7.00%+10.40% | +9.25%-2.29% | +43.65%+28.69% | +60.05%+15.30% | +58.90%-24.55% |
| Flows | BBP HELX | +$4M- | +$26M- | +$30M+$2M | +$42M+$8M | +$45M+$9M | +$38M+$14M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP HELX | +28.75%+26.36% | +24.06%+21.07% | +24.00%+20.62% | +26.36%+23.64% |
| Max drawdown | BBP HELX | -7.49%-6.54% | -9.59%-17.89% | -25.54%-29.16% | -37.87%-58.50% |
| Max drawdown duration | BBP HELX | 37d38d | 48d194d | 292d458d | 760d1739d |
Trading data
BBP | HELX | |
Last sale 6/12/2026 at 1:30 PM | $87.17 | $35.45 |
| Previous close 06/11/2026 | $86.80 | $35.71 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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HELX
is actively managed and doesn’t replicate an indexBBP | HELX | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
BBP | HELX | |
|---|---|---|
| Last price | $87.17 | $35.45 |
| 1D performance | +0.42% | -0.71% |
| AuM | $78.43 M | $23.05 M |
| E/R | 0.79% | 0.5% |
Characteristics
BBP | HELX | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VIRTUS Investment Partners | Franklin Templeton |
| Benchmark | LifeSci Biotechnology Products Index | - |
| N° of holdings | 55 | 50 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | February 25, 2020 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
84.13%
Other
15.87%
HELX
USA
87.65%
Other
12.35%
Sectors
BBP
Health Care
85.97%
Other
14.03%
HELX
Health Care
89.42%
Other
10.58%
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Diversification
BBP
Total weight of top 15 holdings out of 15
45.32%
HELX
Total weight of top 15 holdings out of 15
58.48%
Top 15 holdings
Data as of April 30, 2026
BBP
ARROWHEAD PHARMACEUTICALS INC
3.17%
GB00BRXB0C07
3.17%
BIOGEN INC
3.14%
HALOZYME THERAPEUTICS
3.13%
AURINIA PHARMACEUTICALS INC
3.12%
SYNDAX PHARMACEUTICALS INC
3.12%
BIOMARIN PHARMACEUTICAL
3.05%
INCYTE
3.03%
REGENERON PHARMACEUTICALS
3.03%
BRIDGEBIO PHARMA
3.00%
SAREPTA THERAPEUTICS INC DE
2.95%
ARDELYX
2.92%
VERTEX PHARMACEUTICALS
2.85%
US07725L1026
2.83%
THERAVANCE BIOPHARMA
2.80%
HELX
NATERA
6.86%
GUARDANT HEALTH INC
6.56%
KRYSTAL BIOTECH INC
5.67%
UTD THERAPEUT
4.48%
LIGAND PHARMACEUTICALS
4.31%
BRIDGEBIO PHARMA
4.28%
INSMED
3.80%
ASTRAZENECA
3.26%
ADAPTIVE BIOTECHNOLOGIES
3.23%
SAMSUNG BIOLOGICS CO LTD
3.14%
VERTEX PHARMACEUTICALS
2.87%
REGENERON PHARMACEUTICALS
2.60%
CORTEVA INC
2.58%
ALNYLAM PHARMACEUTICALS
2.44%
LILLY
2.39%
Frequently asked questions about BBP and HELX
How have the BBP and HELX ETFs performed in 2026?
As of June 12, 2026, BBP is up 9.25% year-to-date (YTD), while HELX has lost -2.29%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or HELX?
Year-to-date, the BBP ETF saw +$30M in flows, compared to +$2M for HELX.
Which ETF is more volatile: BBP or HELX?
Over the past year, BBP had a volatility of 24.06%, while HELX experienced 21.07%.
Which ETF is bigger: BBP or HELX?
As of June 12, 2026, BBP holds $78.43 M in assets under management (AUM), while HELX manages $23.05 M.
What sectors do the BBP and HELX ETFs invest in?
BBP leans toward sectors like Health Care. Meanwhile, HELX focuses on Health Care.
What are the top holdings of the BBP ETF and HELX ETF?
BBP top holdings include ARROWHEAD PHARMACEUTICALS INC, GB00BRXB0C07 and BIOGEN INC. HELX holds in its top three: NATERA, GUARDANT HEALTH INC and KRYSTAL BIOTECH INC.
Which ETF is more diversified: BBP or HELX?
BBP holds 59 securities with 45.32% of its assets in the top 15. HELX has 60 securities and a top 15 weight of 58.48%.
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