BBPvsFMEDETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) belongs to the Tomorrow's Treatments segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. Both ETFs have the same top 1 sector exposures: Healthcare. BBP is less expensive with a Total Expense Ratio (TER) of 0.34%, versus 0.5% for FMED. BBP is up 28.37% year-to-date (YTD) with +$66M in YTD flows. FMED performs worse with 17.47% YTD performance, and -$17M in YTD flows. Run a side-by-side ETF comparison of BBP and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs FMED performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/26/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP FMED | -2.65%-1.49% | +5.62%+12.10% | +28.37%+17.47% | +38.01%+18.60% | +119.28%+58.07% | +100.33%n/a |
| Flows | BBP FMED | -- | +$26M- | +$66M-$17M | +$78M-$14M | +$83M-$12M | +$76M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP FMED | +28.32%+27.27% | +26.44%+22.51% | +24.98%+19.68% | +26.86%n/a |
| Max drawdown | BBP FMED | -8.70%-7.63% | -9.59%-17.78% | -25.54%-19.20% | -37.61%n/a |
| Max drawdown duration | BBP FMED | 68d68d | 48d212d | 292d267d | 586dn/a |
Trading data
BBP | FMED | |
Last sale 10/27/2026 at 1:30 PM | $104.89 | |
| Previous close 10/26/2026 | $102.33 | |
| Consolidated volume 10/26/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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FMED
is actively managed and doesn’t replicate an indexBBP | FMED | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/27/2026 at 1:30 PM
Live
Closed
BBP | FMED | |
|---|---|---|
| Last price | $104.89 | – |
| 1D performance | +2.50% | – |
| AuM | $127.99 M | $51.68 M |
| E/R | 0.34% | 0.5% |
Characteristics
BBP | FMED | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VIRTUS Investment Partners | Fidelity |
| Benchmark | LifeSci Biotechnology Products Index | - |
| N° of holdings | 66 | 72 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | June 12, 2023 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
85.98%
Other
14.02%
FMED
USA
84.16%
Other
15.84%
Sectors
BBP
Healthcare
98.44%
Other
1.56%
FMED
Healthcare
99.46%
Other
0.54%
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Diversification
BBP
Total weight of top 15 holdings out of 15
31.08%
FMED
Total weight of top 15 holdings out of 15
44.52%
Top 15 holdings
Data as of August 31, 2026
BBP
Moderna, Inc.
3.58%
Crinetics Pharmaceuticals, Inc.
2.94%
Omeros Corp.
2.49%
Iovance Biotherapeutics, Inc.
2.36%
Verastem, Inc.
2.15%
Precigen, Inc.
1.99%
Halozyme Therapeutics, Inc.
1.84%
Zai Lab Ltd.
1.82%
Kiniksa Pharmaceuticals International Plc
1.81%
Kura Oncology, Inc.
1.72%
BeOne Medicines Ltd.
1.70%
Rigel Pharmaceuticals, Inc.
1.69%
Nuvation Bio, Inc.
1.69%
ACADIA Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
FMED
10X Genomics, Inc.
5.14%
Thermo Fisher Scientific, Inc.
3.89%
Danaher Corp.
3.80%
Natera, Inc.
3.36%
argenx SE
3.18%
Lifestance Health Group, Inc.
3.00%
Revolution Medicines, Inc.
2.92%
Illumina, Inc.
2.86%
Moderna, Inc.
2.69%
Sartorius Stedim Biotech SA
2.59%
HeartFlow, Inc.
2.47%
Alnylam Pharmaceuticals, Inc.
2.31%
Cogent Biosciences, Inc.
2.30%
Intuitive Surgical, Inc.
2.03%
Kymera Therapeutics, Inc.
1.96%
Frequently asked questions about BBP and FMED
How have the BBP and FMED ETFs performed in 2026?
As of October 26, 2026, BBP is up 28.37% year-to-date (YTD), while FMED has returned 17.47%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or FMED?
Year-to-date, the BBP ETF saw +$66M in flows, compared to -$17M for FMED.
Which ETF is more volatile: BBP or FMED?
Over the past year, BBP had a volatility of 26.44%, while FMED experienced 22.51%.
Which ETF is bigger: BBP or FMED?
As of October 26, 2026, BBP holds $127.99 M in assets under management (AUM), while FMED manages $51.68 M.
What sectors do the BBP and FMED ETFs invest in?
BBP leans toward sectors like Healthcare. Meanwhile, FMED focuses on Healthcare.
What are the top holdings of the BBP ETF and FMED ETF?
BBP top holdings include Moderna, Inc., Crinetics Pharmaceuticals, Inc. and Omeros Corp.. FMED holds in its top three: 10X Genomics, Inc., Thermo Fisher Scientific, Inc. and Danaher Corp..
Which ETF is more diversified: BBP or FMED?
BBP holds 66 securities with 31.08% of its assets in the top 15. FMED has 72 securities and a top 15 weight of 44.52%.
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