BBHvsXLVIETF Comparison
VS
ETF 2
XLVI
State Street Health Care Select Sector SPDR Premium Income Fund
This fund is part of
Options Strategies
+0.26%
VanEck Biotech ETF (BBH) belongs to the US Health Care segment. State Street Health Care Select Sector SPDR Premium Income Fund (XLVI) is part of the Options Strategies segment. Both ETFs have the same top 3 sector exposures: and Health Care. Both BBH and XLVI have the same Total Expense Ratio (TER) of 0.35%. BBH is down -1.86% year-to-date (YTD) with -$4M in YTD flows. XLVI performs worse with -3.62% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of BBH and XLVI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBH vs XLVI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBH XLVI | +1.88%+0.50% | -7.18%-5.57% | -1.86%-3.62% | +24.34%n/a | +15.09%n/a | -0.59%n/a |
| Flows | BBH XLVI | -$2M+$501K | -$4M+$2M | -$4M+$2M | -$52M- | -$188M- | -$130M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBH XLVI | +20.75%+13.09% | +20.44%n/a | +18.72%n/a | +21.44%n/a |
| Max drawdown | BBH XLVI | -10.45%-8.21% | -10.45%n/a | -22.78%n/a | -39.88%n/a |
| Max drawdown duration | BBH XLVI | 87d54d | 87dn/a | 440dn/a | 1719dn/a |
Trading data
BBH | XLVI | |
Last sale 4/27/2026 at 1:30 PM | $184.15 | $24.56 |
| Previous close 04/24/2026 | $185.67 | $24.65 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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XLVI
is actively managed and doesn’t replicate an indexBBH | XLVI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
BBH | XLVI | |
|---|---|---|
| Last price | $184.15 | $24.56 |
| 1D performance | -0.82% | -0.34% |
| AuM | $365.13 M | $13.04 M |
| E/R | 0.35% | 0.35% |
Characteristics
BBH | XLVI | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VanEck | State Street Investment Management |
| Benchmark | MVIS US Listed Biotech 25 Index | - |
| N° of holdings | 21 | 56 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 20, 2011 | July 30, 2025 |
| ESG | No | No |
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Exposure
Countries
BBH
USA
97.6%
Other
2.4%
XLVI
USA
96.44%
Other
3.56%
Sectors
BBH
Health Care
89.52%
Other
10.48%
XLVI
Health Care
97.46%
Other
2.54%
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Diversification
BBH
Total weight of top 15 holdings out of 15
86.44%
XLVI
Total weight of top 15 holdings out of 15
70.36%
Top 15 holdings
Data as of March 31, 2026
BBH
AMGEN-T
14.84%
GILEAD SCIENCES
14.71%
VERTEX PHARMACEUTICALS
8.23%
REGENERON PHARMACEUTICALS
7.49%
US04016X1019
5.23%
INSMED
4.42%
IQVIA HOLDINGS INC
4.30%
ALNYLAM PHARMACEUTICALS
4.04%
BIOGEN INC
3.92%
UTD THERAPEUT
3.89%
NATERA
3.82%
US07725L1026
3.20%
MODERNA INC
3.03%
REVOLUTION MEDICINES INC
2.81%
ILLUMINA
2.51%
XLVI
LILLY
13.62%
JOHNSON&JOHNSON
11.01%
ABBVIE
7.19%
MERCK & CO INC
5.58%
UNITEDHEALTH GRP
4.58%
AMGEN-T
3.54%
THERMO FISHER SCIENTIFIC
3.45%
ABBOTT LABS
3.34%
GILEAD SCIENCES
3.23%
INTUITIVE SURGICAL
3.06%
PFIZER
2.98%
BRISTOL-MYERS SQUIBB
2.31%
DANAHER
2.23%
VERTEX PHARMACEUTICALS
2.12%
STRYKER
2.12%
Frequently asked questions about BBH and XLVI
How have the BBH and XLVI ETFs performed in 2026?
As of April 24, 2026, BBH is down -1.86% year-to-date (YTD), while XLVI has lost -3.62%. That puts BBH better performer ahead so far this year.
Which ETF is attracting more investor money: BBH or XLVI?
Year-to-date, the BBH ETF saw -$4M in flows, compared to +$2M for XLVI.
Which ETF is bigger: BBH or XLVI?
As of April 24, 2026, BBH holds $365.13 M in assets under management (AUM), while XLVI manages $13.04 M.
What sectors do the BBH and XLVI ETFs invest in?
BBH leans toward sectors like Health Care. Meanwhile, XLVI focuses on Health Care.
What are the top holdings of the BBH ETF and XLVI ETF?
BBH top holdings include AMGEN-T, GILEAD SCIENCES and VERTEX PHARMACEUTICALS. XLVI holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.
Which ETF is more diversified: BBH or XLVI?
BBH holds 24 securities with 86.44% of its assets in the top 15. XLVI has 59 securities and a top 15 weight of 70.36%.
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