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ARKGvsXHEETF Comparison

ETF 1

ARKG

ARK Genomic Revolution ETF

This fund is part of

BioTech & Genomics

-0.01%

Full ARKG fund page

VS

ETF 2

XHE

State Street SPDR S&P Health Care Equipment ETF

This fund is part of

US Health Care

-0.5%

Full XHE fund page

ARK Genomic Revolution ETF (ARKG) belongs to the BioTech & Genomics segment. State Street SPDR S&P Health Care Equipment ETF (XHE) is part of the US Health Care segment. ARKG's top 3 sector exposures are Health Care and Information Technology. In contrast, XHE's top sector exposures are Health Care ARKG is more expensive with a Total Expense Ratio (TER) of 0.75%, versus 0.35% for XHE. ARKG is down -2.36% year-to-date (YTD) with -$17M in YTD flows. XHE performs worse with -7.32% YTD performance, and -$12M in YTD flows. Run a side-by-side ETF comparison of ARKG and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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ARKG vs XHE performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/29/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	ARKG XHE	+14.98%+3.90%	-9.13%-5.37%	-2.36%-7.32%	+27.92%+3.60%	-2.43%-16.69%	-67.96%-34.99%
Flows	ARKG XHE	-$2M-$10M	-$53M-$8M	-$17M-$12M	-$66M-$41M	-$583M-$308M	-$3.03B-$410M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	ARKG XHE	+43.08%+25.14%	+41.66%+21.83%	+42.62%+21.49%	+45.37%+24.41%
Max drawdown	ARKG XHE	-20.97%-14.31%	-27.52%-18.20%	-51.98%-32.46%	-80.16%-49.90%
Max drawdown duration	ARKG XHE	90d64d	97d113d	1015d1019d	1765d1702d

Trading data

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	ARKG	XHE
Last sale 5/1/2026 at 1:30 PM	$30.30	$81.67
Previous close 04/29/2026	$29.87	$80.33
Consolidated volume 04/29/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of April 30, 2026

1-year trailing difference

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ARKG

is actively managed and doesn’t replicate an index

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	ARKG	XHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 5/1/2026 at 1:30 PM

Live

Closed

	ARKG	XHE
Last price	$30.30	$81.67
1D performance	+1.44%	+1.67%
AuM	$1.13 B	$130.68 M
E/R	0.75%	0.35%

Characteristics

	ARKG	XHE
Management strategy	Active	Passive
Provider	Ark Investment	State Street Investment Management
Benchmark	-	S&P Health Care Equipment Select Industry Index
N° of holdings	27	61
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	April 2, 2019	January 26, 2011
ESG	No	No

More ARKG data on Trackinsight

More XHE data on Trackinsight

Exposure

Countries

ARKG

USA

70.4%

Switzerland

9.23%

Other

20.37%

XHE

USA

92.19%

Other

7.81%

Sectors

ARKG

Health Care

78.38%

Other

21.62%

XHE

Health Care

89.87%

Other

10.13%

Diversification

ARKG

Total weight of top 15 holdings out of 15

62.5%

XHE

Total weight of top 15 holdings out of 15

26.74%

Top 15 holdings

Data as of March 31, 2026

ARKG

CRISPR THERAPEUTICS

9.23%

10X GENOMICS INC

6.30%

BEAM THERAPEUTICS

4.86%

PERSONALIS INC

4.69%

NATERA

4.48%

ILLUMINA

4.45%

GUARDANT HEALTH INC

4.21%

INTELLIA THERAPEUTICS INC

3.58%

CAREDX INC/D

3.56%

RECURSION PHARMACEUTICALS

3.54%

ABSCI

3.27%

VERACYTE INC/D

2.98%

ADAPTIVE BIOTECHNOLOGIES

2.71%

NURIX THERAPEUTICS

2.45%

SEMA4 HOLDINGS CORP

2.19%

XHE

TELEFLEX

1.86%

STAAR SURGICAL

1.84%

BUTTERFLY NETWORK INC

1.84%

US58507V1070

1.83%

GLAUKOS

1.82%

INTEGER HOLDINGS

1.79%

AXOGEN

1.79%

LIVANOVA

1.78%

MASIMO

1.76%

LEMAITRE VASCULAR

1.75%

ARTIVION INC

1.75%

HOLOGIC

1.74%

STERIS

1.74%

GLOBUS MEDICAL

1.72%

IRHYTHM TECHNOLOGIES

1.72%

Frequently asked questions about ARKG and XHE

How have the ARKG and XHE ETFs performed in 2026?

As of April 29, 2026, ARKG is down -2.36% year-to-date (YTD), while XHE has lost -7.32%. That puts ARKG better performer ahead so far this year.

Which ETF is attracting more investor money: ARKG or XHE?

Year-to-date, the ARKG ETF saw -$17M in flows, compared to -$12M for XHE.

Which ETF is more volatile: ARKG or XHE?

Over the past year, ARKG had a volatility of 41.66%, while XHE experienced 21.83%.

Which ETF is bigger: ARKG or XHE?

As of April 29, 2026, ARKG holds $1.13 B in assets under management (AUM), while XHE manages $130.68 M.

What sectors do the ARKG and XHE ETFs invest in?

ARKG leans toward sectors like Health Care. Meanwhile, XHE focuses on Health Care.

What are the top holdings of the ARKG ETF and XHE ETF?

ARKG top holdings include CRISPR THERAPEUTICS, 10X GENOMICS INC and BEAM THERAPEUTICS. XHE holds in its top three: TELEFLEX, STAAR SURGICAL and BUTTERFLY NETWORK INC.

Which ETF is more diversified: ARKG or XHE?

ARKG holds 27 securities with 62.5% of its assets in the top 15. XHE has 67 securities and a top 15 weight of 26.74%.

Biotech ETFs – Investing in Health Innovation

July 21, 2022

ARKG

ARKGvsXHEETF Comparison

ARK Genomic Revolution ETF

State Street SPDR S&P Health Care Equipment ETF

ARKG vs XHE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the ARKG and XHE ETFs performed in 2026?

As of April 29, 2026, ARKG is down -2.36% year-to-date (YTD), while XHE has lost -7.32%. That puts ARKG better performer ahead so far this year.

Which ETF is attracting more investor money: ARKG or XHE?

Year-to-date, the ARKG ETF saw -$17M in flows, compared to -$12M for XHE.

Which ETF is more volatile: ARKG or XHE?

Over the past year, ARKG had a volatility of 41.66%, while XHE experienced 21.83%.

Which ETF is bigger: ARKG or XHE?

As of April 29, 2026, ARKG holds $1.13 B in assets under management (AUM), while XHE manages $130.68 M.

What sectors do the ARKG and XHE ETFs invest in?

ARKG leans toward sectors like Health Care. Meanwhile, XHE focuses on Health Care.

What are the top holdings of the ARKG ETF and XHE ETF?

ARKG top holdings include CRISPR THERAPEUTICS, 10X GENOMICS INC and BEAM THERAPEUTICS. XHE holds in its top three: TELEFLEX, STAAR SURGICAL and BUTTERFLY NETWORK INC.

Which ETF is more diversified: ARKG or XHE?

ARKG holds 27 securities with 62.5% of its assets in the top 15. XHE has 67 securities and a top 15 weight of 26.74%.

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