ARKGvsIBRNETF Comparison
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ARK Genomic Revolution ETF (ARKG) belongs to the BioTech & Genomics segment. iShares Neuroscience and Healthcare ETF (IBRN) is part of the Healthcare Technology segment. Both ETFs have the same top 3 sector exposures: and Healthcare. ARKG is more expensive with a Total Expense Ratio (TER) of 0.75%, versus 0.47% for IBRN. ARKG is up 29.47% year-to-date (YTD) with +$39M in YTD flows. IBRN performs worse with 16.7% YTD performance, and - in YTD flows. Run a side-by-side ETF comparison of ARKG and IBRN below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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ARKG vs IBRN performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | ARKG IBRN | -1.87%+1.23% | +27.92%+9.21% | +29.47%+16.70% | +45.31%+63.17% | +4.16%+56.08% | -54.66%n/a |
| Flows | ARKG IBRN | +$81M- | +$62M- | +$39M- | -$3M- | -$550M-$1M | -$2.57B- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | ARKG IBRN | +44.86%+24.90% | +42.64%+25.46% | +43.40%+24.99% | +45.98%n/a |
| Max drawdown | ARKG IBRN | -13.14%-8.16% | -27.52%-8.68% | -51.67%-34.98% | -79.29%n/a |
| Max drawdown duration | ARKG IBRN | 18d15d | 126d75d | 1058d338d | 1814dn/a |
Trading data
ARKG | IBRN | |
Last sale 7/27/2026 at 1:30 PM | $37.75 | $37.82 |
| Previous close 07/24/2026 | $37.81 | $37.69 |
| Consolidated volume 07/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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ARKG
is actively managed and doesn’t replicate an indexARKG | IBRN | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/27/2026 at 1:30 PM
Live
Closed
ARKG | IBRN | |
|---|---|---|
| Last price | $37.75 | $37.82 |
| 1D performance | -0.16% | +0.34% |
| AuM | $1.53 B | $5.66 M |
| E/R | 0.75% | 0.47% |
Characteristics
ARKG | IBRN | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Ark Investment | iShares |
| Benchmark | - | NYSE FactSet Global Neuro Biopharma and MedTech Index |
| N° of holdings | 31 | 70 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 2, 2019 | August 24, 2022 |
| ESG | No | No |
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Exposure
Countries
ARKG
USA
86.99%
Other
13.01%
IBRN
USA
77.98%
Other
22.02%
Sectors
ARKG
Healthcare
96.93%
Other
3.07%
IBRN
Healthcare
99.9%
Other
0.1%
Diversification
ARKG
Total weight of top 15 holdings out of 15
74.95%
IBRN
Total weight of top 15 holdings out of 15
60.92%
Top 15 holdings
Data as of June 30, 2026
ARKG
Twist Bioscience Corp.
9.15%
Tempus AI, Inc.
7.64%
Absci Corp.
7.01%
10X Genomics, Inc.
7.00%
CRISPR Therapeutics AG
6.56%
Personalis, Inc.
6.19%
Beam Therapeutics, Inc.
4.34%
Guardant Health, Inc.
4.28%
Natera, Inc.
4.11%
Illumina, Inc.
3.98%
Veracyte, Inc.
3.24%
CareDx, Inc.
3.08%
Recursion Pharmaceuticals, Inc.
2.85%
Eli Lilly & Co.
2.81%
Compass Pathways Plc
2.70%
IBRN
Praxis Precision Medicines, Inc.
4.79%
Scholar Rock Holding Corp.
4.53%
Alkermes Plc
4.47%
Dianthus Therapeutics, Inc.
4.42%
Xenon Pharmaceuticals, Inc.
4.26%
PTC Therapeutics, Inc.
4.20%
ACADIA Pharmaceuticals, Inc.
4.17%
Arrowhead Pharmaceuticals, Inc.
4.07%
Biogen, Inc.
4.04%
Axsome Therapeutics, Inc.
3.85%
argenx SE
3.80%
Neurocrine Biosciences, Inc.
3.76%
Denali Therapeutics, Inc.
3.73%
Catalyst Pharmaceuticals, Inc.
3.42%
BlackRock Cash Funds - Treasury
3.40%
Frequently asked questions about ARKG and IBRN
How have the ARKG and IBRN ETFs performed in 2026?
As of July 24, 2026, ARKG is up 29.47% year-to-date (YTD), while IBRN has returned 16.7%. That puts ARKG better performer ahead so far this year.
Which ETF is attracting more investor money: ARKG or IBRN?
Year-to-date, the ARKG ETF saw +$39M in flows, compared to - for IBRN.
Which ETF is more volatile: ARKG or IBRN?
Over the past year, ARKG had a volatility of 42.64%, while IBRN experienced 25.46%.
Which ETF is bigger: ARKG or IBRN?
As of July 24, 2026, ARKG holds $1.53 B in assets under management (AUM), while IBRN manages $5.66 M.
What sectors do the ARKG and IBRN ETFs invest in?
ARKG leans toward sectors like Healthcare. Meanwhile, IBRN focuses on Healthcare.
What are the top holdings of the ARKG ETF and IBRN ETF?
ARKG top holdings include Twist Bioscience Corp., Tempus AI, Inc. and Absci Corp.. IBRN holds in its top three: Praxis Precision Medicines, Inc., Scholar Rock Holding Corp. and Alkermes Plc.
Which ETF is more diversified: ARKG or IBRN?
ARKG holds 31 securities with 74.95% of its assets in the top 15. IBRN has 70 securities and a top 15 weight of 60.92%.
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Latest news about ARKG & IBRN
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