ARKGvsFMEDETF Comparison
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ARK Genomic Revolution ETF (ARKG) belongs to the BioTech & Genomics segment. Fidelity Disruptive Medicine ETF (FMED) is part of the Multiple Trends segment. Both ETFs have the same top 1 sector exposures: Healthcare. ARKG is more expensive with a Total Expense Ratio (TER) of 0.75%, versus 0.5% for FMED. ARKG is up 76.72% year-to-date (YTD) with +$90M in YTD flows. FMED performs worse with 20.13% YTD performance, and -$17M in YTD flows. Run a side-by-side ETF comparison of ARKG and FMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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ARKG vs FMED performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | ARKG FMED | -3.25%+0.74% | +36.71%+14.65% | +76.72%+20.13% | +65.56%+21.30% | +132.21%+63.57% | -29.90%n/a |
| Flows | ARKG FMED | +$37M- | +$51M- | +$90M-$17M | +$63M-$14M | -$431M-$12M | -$2.01B- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | ARKG FMED | +49.99%+27.37% | +44.59%+22.57% | +44.73%+19.71% | +46.89%n/a |
| Max drawdown | ARKG FMED | -17.81%-7.63% | -27.52%-17.78% | -46.41%-19.20% | -76.56%n/a |
| Max drawdown duration | ARKG FMED | 22d69d | 126d212d | 882d267d | 1818dn/a |
Trading data
ARKG | FMED | |
Last sale 10/28/2026 at 1:30 PM | $54.82 | |
| Previous close 10/27/2026 | $51.65 | |
| Consolidated volume 10/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 10/28/2026 at 1:30 PM
Live
Closed
ARKG | FMED | |
|---|---|---|
| Last price | $54.82 | – |
| 1D performance | +6.14% | – |
| AuM | $2.18 B | $52.85 M |
| E/R | 0.75% | 0.5% |
Characteristics
ARKG | FMED | |
|---|---|---|
| Management strategy | Active | Active |
| Provider | Ark Investment | Fidelity |
| Benchmark | - | - |
| N° of holdings | 31 | 72 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 2, 2019 | June 12, 2023 |
| ESG | No | No |
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Exposure
Countries
ARKG
USA
88.62%
Other
11.38%
FMED
USA
84.16%
Other
15.84%
Sectors
ARKG
Healthcare
97.89%
Other
2.11%
FMED
Healthcare
99.46%
Other
0.54%
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Diversification
ARKG
Total weight of top 15 holdings out of 15
74.64%
FMED
Total weight of top 15 holdings out of 15
44.52%
Top 15 holdings
Data as of August 31, 2026
ARKG
10X Genomics, Inc.
9.58%
Twist Bioscience Corp.
9.13%
Tempus AI, Inc.
7.91%
CRISPR Therapeutics AG
6.10%
Personalis, Inc.
5.93%
Absci Corp.
4.88%
Natera, Inc.
4.06%
Illumina, Inc.
4.04%
Eli Lilly & Co.
3.86%
CareDx, Inc.
3.85%
Guardant Health, Inc.
3.81%
Beam Therapeutics, Inc.
3.56%
Compass Pathways Plc
3.17%
Recursion Pharmaceuticals, Inc.
2.44%
Adaptive Biotechnologies Corp.
2.32%
FMED
10X Genomics, Inc.
5.14%
Thermo Fisher Scientific, Inc.
3.89%
Danaher Corp.
3.80%
Natera, Inc.
3.36%
argenx SE
3.18%
Lifestance Health Group, Inc.
3.00%
Revolution Medicines, Inc.
2.92%
Illumina, Inc.
2.86%
Moderna, Inc.
2.69%
Sartorius Stedim Biotech SA
2.59%
HeartFlow, Inc.
2.47%
Alnylam Pharmaceuticals, Inc.
2.31%
Cogent Biosciences, Inc.
2.30%
Intuitive Surgical, Inc.
2.03%
Kymera Therapeutics, Inc.
1.96%
Frequently asked questions about ARKG and FMED
How have the ARKG and FMED ETFs performed in 2026?
As of October 27, 2026, ARKG is up 76.72% year-to-date (YTD), while FMED has returned 20.13%. That puts ARKG better performer ahead so far this year.
Which ETF is attracting more investor money: ARKG or FMED?
Year-to-date, the ARKG ETF saw +$90M in flows, compared to -$17M for FMED.
Which ETF is more volatile: ARKG or FMED?
Over the past year, ARKG had a volatility of 44.59%, while FMED experienced 22.57%.
Which ETF is bigger: ARKG or FMED?
As of October 27, 2026, ARKG holds $2.18 B in assets under management (AUM), while FMED manages $52.85 M.
What sectors do the ARKG and FMED ETFs invest in?
ARKG leans toward sectors like Healthcare. Meanwhile, FMED focuses on Healthcare.
What are the top holdings of the ARKG ETF and FMED ETF?
ARKG top holdings include 10X Genomics, Inc., Twist Bioscience Corp. and Tempus AI, Inc.. FMED holds in its top three: 10X Genomics, Inc., Thermo Fisher Scientific, Inc. and Danaher Corp..
Which ETF is more diversified: ARKG or FMED?
ARKG holds 31 securities with 74.64% of its assets in the top 15. FMED has 72 securities and a top 15 weight of 44.52%.
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Latest news about ARKG & FMED
The Weekly ETF Market Monitor (October 19-23, 2026)
October 26, 2026
ARKG
Biotech ETFs – Investing in Health Innovation
July 21, 2022
ARKG
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